We are studying RNA silencing in the model organism Arabidopsis thaliana and several economically-important crops.
RNA silencing is a key regulatory process that controls various aspects of biology in eukaryotes including growth and development, antiviral defense and chromosome gardening. The common themes under RNA silencing include the biogenesis of small RNAs by DICERs or Dicer-like proteins and the incorporation of the small RNAs into Argonaute (AGO)-centered RNA-induced silencing complexes (RISCs).
The RISCs execute the repressive or regulatory functions on target genes at the transcriptional or post-transcriptional levels. Our long-term goals are to understand novel functions and mechanisms of RNA silencing in plants.
Get in touch
Norman Borlaug Center for Southern Crop Improvement